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Application of diethyl ethynylphosphonate to the synthesis of 3‐phosphonylated β‐lactams via the Kinugasa reaction
(ARKAT USA, 2017)
The easily available diethyl ethynylphosphonate reacts with diverse aldonitrones under Kinugasa reaction conditions at room temperature, providing 3‐phosphonylated β‐lactams in good yields. In all cases, the reaction ...