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Bioinsektycyd Beauveria bassiana jako mikrobiologiczny czynnik eliminujący mykotoksyny fuzaryjne - MINIATURA 7 (2023/07/X/NZ9/00547)
(2024)During the implementation of the scientific project activity, the growth and sporulation of the entomopathogenic fungus Beauveria bassiana ASREF 2860 were assessed in the presence of Fusarium mycotoxins. Additionally, the ... -
Role of the PARP1/HPF1 complex in the conferring of resistance to doxorubicin in triple negative breast cancer (dataset)
(2023-02-15)Multidrug resistance (MDR) is characterized, inter alia, by overexpression of ABC transporters responsible for the removal of drugs outside the cell and their sequestration in intracellular organelles. Considering that ... -
Pochodne pirazolin skondensowane z chromanonem lub flawanonem w terapii raka jelita grubego: analiza molekularnych aktywności przeciwnowotworowych. - Miniatura 7 2023/07/X/NZ3/01404 (dataset)
(2024)This study investigated the anticancer potential of six flavanone/chromanone derivatives on five human colorectal cancer cell lines (HCT 116, SW620, LoVo, Caco-2, HT-29). Cytotoxicity assays (MTT) revealed that three ... -
Effect of light conditions, Trichoderma fungi and food polymers on growth and profile of biologically active compounds in Thymus vulgaris and Thymus serpyllum (dataset)
(2024-04-29)The research investigates the influence of different lighting conditions and soil treatments, in particular the application of food polymers separately and in combination with spores of Trichoderma consortium, on the ... -
Nanocząstki polistyrenowe i ich właściwości epigenetyczne i genotoksyczne w ludzkich jednojądrzastych komórkach krwi obwodowej - PRELUDIUM-20 nr 2021/41/N/NZ7/02049 (dataset)
(2024)Celem kolejnej części projektu było określenie wpływu krótkotrwałej ekspozycji niefunkcjonalizowanych nanocząstek polistyrenowych (PS-NP) o różnych średnicach 29, 44 i 72 nm na metylację DNA i ekspresję genów w jednojądrzastych ... -
Unveiling a Novel Zearalenone Biodegradation Pathway in Metarhizium anisopliae and Elucidating the Role of Cytochrome P450 (dataset)
(2023-01-25)Metarhizium fungi, essential for ecosystem function and commonly utilised in pest control, often occupy ecological niches contaminated by toxic compounds of both anthropogenic and microbi-ological origin. The present study ... -
Does a lower dosage of sewage sludge affect the microbiome and resistome of agricultural soils?
(2025-03)Amendment of soils with sewage sludge are a common practice in agriculture to improve crop yields. Sewage sludge could carry hazardous elements, including prokaryotes that are resistant to antibiotics and heavy metals. ... -
Olaparib Combined with DDR Inhibitors Effectively Prevents EMT and Affects miRNA Regulation in TP53-Mutated Epithelial Ovarian Cancer Cell Lines
(2025)Epithelial ovarian cancer (EOC) remains a leading cause of gynecologic cancer mortality. Despite advances in treatment, metastatic progression and resistance to standard therapies significantly worsen patient outcomes. ... -
Data_Sewage sludge fertilization affects microbial community structure and its resistome in agricultural soils (dataset)
(2025-01-01)Global sewage sludge production is rapidly increasing, and its safe disposal is becoming an increasingly serious issue. One of the main methods of municipal sewage sludge management is based on its agricultural use. The ... -
Data: Impact of aged turkey manure on soil‒plant health: uncovering shifts in microbial diversity and antibiotic resistance genes (dataset)
(2025)This study examines how aged turkey manure affects soil physicochemical properties, microbial diversity, and the distribution of antibiotic resistance genes (ARGs) in the soil‒plant system. The soil properties changed ... -
Data: Game changer? Benomyl as a modulator of paracetamol bioaccumulation and endophytic microbiome diversity in zucchini (dataset)
(2025)Background: Paracetamol, a widely used analgesic and antipyretic, has emerged as a prevalent environmental pollutant that poses risks to various organisms, including plants. Phytoremediation, particularly the use of ... -
Videos for Kok et al 2024 Lost in space and time (dataset)
(2024-10-11) -
Induction of expression of genes responsible for biodegradation of MCPA by selected plant secondary metabollites (dataset)
(2025)The main aim of this PRELUDIUM 20 project was to assess the impact of selected PSMs, i.e. syringic acid, caffeic acid, vanillic acid and salicylic acid on: (1) the expression of functional genes responsible for the initial ... -
Molecular mechanisms restoring olaparib efficacy through ATR/CHK1 pathway inhibition in olaparib-resistant BRCA1/2MUT ovarian cancer models (dataset)
(2024)Resistance to olaparib inevitably develops in ovarian cancer (OC) patients, highlighting the necessity for effective strategies to improve its efficacy. Here, we established a novel olaparib-resistant patient-derived ... -
Nowe pochodne benserazydu i benitrobenrazydu w terapii raka piersi - wstępna analiza aktywności biologicznej in vitro (dataset)
(2024)The research focused on identifying new methods for treating breast cancer, one of the most common cancers in women. Benserazide, benitrobenrazide, and their derivatives were tested on two cancer cell lines (MCF-7 and ... -
Zmiany zespołów mikroorganizmów, oporności na antybiotyki i właściwości fizykochemicznych gleby nawożonej komunalnymi osadami ściekowymi
(2023)The overuse of soil, for example by intensive agricultural practices, causes soil erosion, desertification and deterioration, and makes the soil inaccessible to future generations as a resource. One possible way to reverse ... -
Crosslinked hybrid polymer/ceramic composite coatings for controlled release of clindamycin - dataset
Urbaniak, Mateusz M.
; Tomaszewska, Agata ; ; Szwed-Georgiou, Aleksandra ; (2024-08-07)
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Characterization of the Uterine Microbiome in Endometrial Cancer Patients and Identification of the genus Anaerococcus as a Potential Indicator of EC and a Possible Carcinogenic Cofactor. SONATA-17 2021/43/D/NZ7/01386 (dataset)
Kowalczyk, Aleksandra; ; (2024)
The advent of sequencing techniques has facilitated the application of microbiome studies in cancer research. It has been observed that microbial pathogens contribute to tumorigenesis in a significant portion of reported ... -
Uncovering miRNA-mRNA Regulatory Networks Related to Olaparib Resistance and Resensitization of BRCA2MUT Ovarian Cancer PEO1-OR Cells with the ATR/CHK1 Pathway Inhibitors, Sonata Bis 2019/34/E/NZ7/00056, Sonata Bis-9 (dataset)
(2024)Resistance to olaparib is the major obstacle in targeted therapy for ovarian cancer (OC) with poly(ADP-ribose) polymerase inhibitors (PARPis), prompting studies on novel combination therapies to enhance olaparib efficacy. ...