The main focus of the paper is to indicate the impact and significance of the location of transport hubs and road’s network for the location of logistics centres. The analysis was based on existing and constructed roads’ (regional, national and international level) data. Therefore, it was possible to determine the influence of the transport hubs, international and local transport policy on previous location decisions. Authors identified optimal locations of logistic centres in the Łódź region. Furthermore, authors assessed the location decisions and their determinants. Finally, universal recommendations for the development of the regional transport network have been formulated. This work was partially founded by the Municipality of Łódź. The study focused on the characteristics and trends of development of intermodal logistics centres in the context of the operation of the Trans-European Transport Network (TEN-T) in the Łódź region, particularly in the Łódź Metropolitan Area.