Znaczenie erytrocytów w aktywacji płytek krwi
Streszczenie
The blood platelet activation plays an important role in haemostasis. Mechanism of
platelet activation is accompanied by intracellular signal transduction pathways that are
responsible for different physiological responses of platelets: changes in platelet shape, release
of their granule contents and platelet aggregation. Platelets circulate in vivo together with huge
masses of erythrocytes and some leukocytes. Cell-cell interactions between platelets and
neutrophils or platelets and erythrocytes can significantly alter platelet reactivity. In recent
years demonstrated that erythrocytes may enhance platelet release reaction and eicosanoid
synthesis. Role of erythrocytes in blood platelet activation are described and eicosanoid synthesis.